Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/108199
Type: Artigo de evento
Title: Radiation From Mammography: Diagnostic Or Cancer Induction?
Author: Loureiro C.F.C.L.
Hernandez-Figueroa H.E.
Muhlen S.S.
Bertuzzo C.S.
Abstract: Establishing the biological effects and the safe level of exposure to ionizing radiation remains, so far, an objective to be reached. Mammography is an important exam in the early detection of breast tumors, but since the genes BRCA1 and BRCA2 were identified as a main cause of hereditary breast cancer, there is growing concern of exposing patients carrying those mutations to ionizing radiation. It could increase mutations in these genes and other suppressors, and promote the development of tumor in those patients. In this study we propose an in vitro initial experiment aiming to determine the radiation trigger level for detectable mutations in genes BRCA, and thus a safer level of radiation due to mammography for patients carrying a mutated allele of the genes BRCA1 or BRCA2. Breast cells from one patient were cultivated and irradiated with different doses of X-rays generated by commercial mammography equipment. The results have shown that exposition to ionizing radiation promotes measurable alterations in breast cell grown. © 2011 IEEE.
Editor: 
Rights: fechado
Identifier DOI: 10.1109/IMOC.2011.6169348
Address: http://www.scopus.com/inward/record.url?eid=2-s2.0-84860436174&partnerID=40&md5=e1bc933f36d2a0b51fd2942d2ac083dc
Date Issue: 2011
Appears in Collections:Unicamp - Artigos e Outros Documentos

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