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|Type:||Artigo de periódico|
|Title:||Analysis Of Street Ecstasy Tablets By Thin Layer Chromatography Coupled To Easy Ambient Sonic-spray Ionization Mass Spectrometry|
|Abstract:||Ecstasy is a famous illicit drug with varying drug composition, but it usually contains 3, 4-meth-ylenedioxymethamphetamine (MDMA) as the main active ingredient. The common proce-dure to identify ecstasy tablets uses testing kits, but its low specificity may lead to false posi-tives. Thin layer chromatography (TLC) is used worldwide in forensic investigations due to its simplicity, low-cost and versatility but may also lead to false positives. In this study, TLC sepa-ration of seven common ecstasy drugs: MDMA, metamphetamine, 3, 4-methylenedioxyeth-ylamphetamine (MDEA), 3, 4-methylenedioxyamphetamine (MDA), amphetamine, caffeine and lidocaine was attained, and twenty five apprehended street ecstasy tablets analyzed by TLC. Easy ambient sonic-spray ionization mass spectrometry (EASI-MS) was then performed directly on the surface of each TLC spot for MS characterization. The combination of TLC with EASI-MS is shown to provide a relatively simple and powerful screening tool for forensic analy-sis of street drugs with fast and indisputable results.|
|Appears in Collections:||Unicamp - Artigos e Outros Documentos|
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