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|Type:||Artigo de periódico|
|Title:||The Impact Of Prior Preeclampsia On The Risk Of Superimposed Preeclampsia And Other Adverse Pregnancy Outcomes In Patients With Chronic Hypertension|
Pinto E Silva J.L.
De Barros Santos C.
Spinnato II J.A.
|Abstract:||Objective: We sought to compare the rates of superimposed preeclampsia and adverse outcomes in women with chronic hypertension with or without prior preeclampsia. Study Design: We conducted secondary analysis of 369 women with chronic hypertension (104 with prior preeclampsia) enrolled at 12-19 weeks as part of a multisite trial of antioxidants to prevent preeclampsia (no reduction was found). Outcome measures were rates of superimposed preeclampsia and other adverse perinatal outcomes. Results: Prepregnancy body mass index, blood pressure, and smoking status at enrollment were similar between groups. The rates of superimposed preeclampsia (17.3% vs 17.7%), abruptio placentae (1.0% vs 3.1%), perinatal death (6.7% vs 8.7%), and small for gestational age (18.4% vs 14.3%) were similar between groups, but preterm delivery <37 weeks was higher in the prior preeclampsia group (36.9% vs 27.1%; adjusted risk ratio, 1.46; 95% confidence interval, 1.052.03; P = .032). Conclusion: In women with chronic hypertension, a history of preeclampsia does not increase the rate of superimposed preeclampsia, but is associated with an increased rate of delivery at <37 weeks. © 2011 Published by Mosby, Inc.|
|Appears in Collections:||Unicamp - Artigos e Outros Documentos|
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