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Type: Artigo de periódico
Title: The Impact Of Prior Preeclampsia On The Risk Of Superimposed Preeclampsia And Other Adverse Pregnancy Outcomes In Patients With Chronic Hypertension
Author: Sibai B.M.
Koch M.A.
Freire S.
Pinto E Silva J.L.
Rudge M.V.C.
Martins-Costa S.
Moore J.
De Barros Santos C.
Cecatti J.G.
Costa R.
Ramos J.G.
Moss N.
Spinnato II J.A.
Abstract: Objective: We sought to compare the rates of superimposed preeclampsia and adverse outcomes in women with chronic hypertension with or without prior preeclampsia. Study Design: We conducted secondary analysis of 369 women with chronic hypertension (104 with prior preeclampsia) enrolled at 12-19 weeks as part of a multisite trial of antioxidants to prevent preeclampsia (no reduction was found). Outcome measures were rates of superimposed preeclampsia and other adverse perinatal outcomes. Results: Prepregnancy body mass index, blood pressure, and smoking status at enrollment were similar between groups. The rates of superimposed preeclampsia (17.3% vs 17.7%), abruptio placentae (1.0% vs 3.1%), perinatal death (6.7% vs 8.7%), and small for gestational age (18.4% vs 14.3%) were similar between groups, but preterm delivery <37 weeks was higher in the prior preeclampsia group (36.9% vs 27.1%; adjusted risk ratio, 1.46; 95% confidence interval, 1.052.03; P = .032). Conclusion: In women with chronic hypertension, a history of preeclampsia does not increase the rate of superimposed preeclampsia, but is associated with an increased rate of delivery at <37 weeks. © 2011 Published by Mosby, Inc.
Rights: fechado
Identifier DOI: 10.1016/j.ajog.2010.11.027
Date Issue: 2011
Appears in Collections:Unicamp - Artigos e Outros Documentos

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