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Type: Artigo de periódico
Title: Community Program And G-6-pd Deficiency In Brazil [programa Comunitário E Deficiência De G-6-pd No Brasil]
Author: Compri M.B.
Polimeno N.C.
Vieira M.J.A.
Saad S.T.O.
Ramalho A.S.
Abstract: This study tested the viability and efficiency of a glucose-6-phosphate dehydrogenase deficiency program in which a Brazilian community - the town of Bragança Paulista, SP (Brazil) was involved. The screening was done among blood donors and the diagnosis of glucose-6-phosphate dehydrogenase deficiency was confirmed through enzymatic quantification and through electrophoresis of the enzyme. A total of 4,621 individuals were tested over a period of 36 months. A total of 80 individuals with glucose-6-phosphate dehydrogenase deficiency were detected - 1,7% of the samples examined. The acceptance rate to the optional genetic orientation got to 61% and the percentage of good assimilation concerning the offered information was 81%. The molecular analysis demonstrated the presence, almost exclusive, in the community of the A or African variant, a benign mutation. With a verity low annual cost, it was possible not only to make diagnosis and to advise a significant number of families with glucose-6-phosphate dehydrogenase deficiency, but also to start the education of the community towards this problem.
Rights: aberto
Identifier DOI: 
Date Issue: 2000
Appears in Collections:Unicamp - Artigos e Outros Documentos

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