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Type: Artigo de periódico
Title: Laser Effects On Osteogenesis
Author: Freitas I.G.F.
Baranauskas V.
Cruz-Hofling M.A.
Abstract: The traumatic or surgical cutting of a long bone is immediately followed by a sequence of repair processes in which the osteogenic cells of the periosteum start to proliferate and differentiate in osteoblast cells. In this work, we explored the influence of a He-Ne laser on osteogenesis after a controlled surgical fracture. We used young male adult Wistar rats (of mass between 250 and 300 g). The fracture was provoked by piercing a 2-mm-diameter hole in just one cortical tibia surface. Laser treatment was started 24 h after the surgery. The animals were separated into three groups, for different radiation doses, and after daily applications, they were sacrificed at 8 or 15 days. Light and electron microscopies revealed that the laser treatment of the lesion with doses of 31.5 and 94.7 J cm -2 resulted in the formation of thicker bony trabeculae, which indicates a greater synthesis of collagen fibers and therefore that the osteoblastic activity was increased by the low-energy laser radiation.
Editor: Elsevier Science Publishers B.V., Amsterdam, Netherlands
Rights: fechado
Identifier DOI: 10.1016/S0169-4332(99)00431-6
Date Issue: 2000
Appears in Collections:Unicamp - Artigos e Outros Documentos

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