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Type: Artigo de periódico
Title: Obtaining β-caryophyllene From Cordia Verbenacea De Candolle By Supercritical Fluid Extraction
Author: Quispe-Condori S.
Foglio M.A.
Rosa P.T.V.
Meireles M.A.A.
Abstract: In the present work, the use of supercritical fluid extraction (SFE) to obtain β-caryophyllene from Cordia verbenacea DC was studied. The assays were performed using a single-step SFE (1S-SFE) and a three-step SFE (3S-SFE). In view of the literature results for the biological activities of C. verbenacea, the assays for the 3S-SFE were conducted at 60 °C and pressures of 8, 20, and 30 MPa, while for the 1S-SFE, they were performed at 50 and 60 °C and pressures of 20 and 30 MPa. In the 3S-SFE, three samples of C. verbenacea extract were obtained. The purity of β-caryophyllene was 33% (extract's dry basis) for the fraction obtained at 8 MPa. The kinetics of supercritical CO2 extraction was studied at the optimum operational conditions for global yield and anticancer activity (30 MPa/50 °C and 20 MPa/40 °C, respectively). The effect of bed height on the kinetic parameters of the SFE process was also investigated. Literature models fitted quantitatively the experimental extraction curves. © 2008 Elsevier B.V. All rights reserved.
Rights: fechado
Identifier DOI: 10.1016/j.supflu.2008.02.015
Date Issue: 2008
Appears in Collections:Unicamp - Artigos e Outros Documentos

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