Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/106624
Type: Artigo de periódico
Title: Asbestos-related Disease: Progression Of Parenchymal Abnormalities On High-resolution Ct
Author: Silva C.I.S.
Muller N.L.
Neder J.A.
Nogueira C.R.
Napolis L.M.
Terra-Filho M.
Bagatin E.
Nery L.E.
Abstract: Purpose: To evaluate the changes over time in the pattern and extent of parenchymal abnormalities in asbestos-exposed workers after cessation of exposure and to compare 3 proposed semiquantitative methods with a careful side-by-side comparison of the initial and the follow-up computed tomography (CT) images. Materials and Methods: The study included 52 male asbestos workers (mean age ± SD, 62.2 y ± 8.2) who had baseline high-resolution CT after cessation of exposure and follow-up CT 3 to 5 years later. Two independent thoracic radiologists quantified the findings according to the scoring systems proposed by Huuskonen, Gamsu, and Sette and then did a side-by-side comparison of the 2 sets of scans without awareness of the dates of the CT scans. Results: There was no difference in the prevalence of the 2 most common parenchymal abnormalities (centrilobular small dotlike or branching opacities and interstitial lines) between the initial and follow-up CT scans. Honeycombing (20%) and traction bronchiectasis and bronchiolectasis (50%) were seen more commonly on the follow-up CT than on the initial examination (10% and 33%, respectively) (P = 0.01). Increased extent of parenchymal abnormalities was evident on side-by-side comparison in 42 (81%) patients but resulted in an increase in score in at least 1 semiquantitative system in only 16 (31%) patients (all P > 0.01, signed test). Conclusions: The majority of patients with previous asbestos exposure show evidence of progression of disease on CT at 3 to 5 years follow-up but this progression is usually not detected by the 3 proposed semiquantitative scoring schemes. Copyright © 2008 by Lippincott Williams & Wilkins.
Editor: 
Rights: fechado
Identifier DOI: 10.1097/RTI.0b013e31817e352a
Address: http://www.scopus.com/inward/record.url?eid=2-s2.0-57749209206&partnerID=40&md5=f92200b460aeac13cb974fd397a87577
Date Issue: 2008
Appears in Collections:Unicamp - Artigos e Outros Documentos

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