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Type: Artigo de periódico
Title: Antibiotic Prophylaxis In Elective Laparoscopic Cholecystectomy: A Prospective, Randomized And Double Blind Study [antibioticoprofilaxia Na Colecistectomia Videolaparoscópica Eletiva: Estudo Prospectivo Randomizado E Duplo Cego]
Author: Petry de Souza H.
Breigeiron R.
Moreira da Cunha H.
Deves E.
Abstract: Background: To identify the need for aintibiotic prophylaxis usage in routine laparoscopic cholecystectomy. Methods: A prospective, randomized double-blind study was done in patients submitted to routine laparoscopic cholecystectomy from June 2003 to July 2007, with 163 patients divided in two groups: Group A (n=82) received antibiotic prophylaxis with Cefoxitin 2g IV at anesthesia induction; Group B (n=81) received 2 mL of isotinic sodium chloride solution at same time. Surgical technique and team were the same. The purpose of this study was to search the outcome for surgical site ifections and superficial or deep abscesses. The patients were examined at 7 and 28 days after surgery. Data were analyzed by Fisher's exact test. Results: This study showed infection complication rates of 4.76% in group A and 6.17% in group B. There were no statistical significant differences (p = 0.746) for infection complication rates in both groups. The groups were homogeneous and comparable. Conclusions: Patients submitted to routine laparoscopic cholecystectomy with low surgical risk do not need antibiotic prophylaxis, because it will not result in lower infection rates.
Rights: aberto
Identifier DOI: 
Date Issue: 2008
Appears in Collections:Unicamp - Artigos e Outros Documentos

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