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|Type:||Artigo de periódico|
|Title:||Genetic Polymorphisms Determining Of The Physical Performance In Elite Athletes [polimorfismos Genéticos Determinantes Da Performance Física Em Atletas De Elite]|
|Abstract:||This article is focused on the review of studies looking for "candidate genes" and their relationship with physical performance phenotypes in elite athletes. Our goal is to bring to readers what makes some individuals excel in some sports modalities, based on variants in genetic loci and markers. In addition, we assume the necessity to describe by what mechanisms a gene can contribute in physical performance, detailing in each part the cellular, physiological and molecular pathways involved. For this reason, we limited our discussion to a small number of genetic variants: polymorphisms R577X α-actinin 3 gene (ACTN3), C34T AMP deaminase gene (AMPD1), I/D angiotensin converting enzyme gene (ACE), -9/+9 β 2 bradykinin receptor gene (BDKRB2), and 985+185/1170 creatine kinase M gene (CK-M). We hope that this article bring some new information and refine the knowledge to the fact that the process of talent identification and an individual athletic potential maximization resulting in sport success are strongly associated with genetic variants.|
|Appears in Collections:||Unicamp - Artigos e Outros Documentos|
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