Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/104606
Type: Artigo de periódico
Title: Viability Of Nerve Grafts Preserved In Different Storage Medium
Author: Carone A.L.
Scabora J.E.
Barros B.R.
Esquisatto M.A.M.
Figueiredo J.F.
Langone F.
Abstract: We compared the structural features of nerve segments stored in two different solutions previous and after autologous transplantation. Male Wistar rats were divided into groups to obtain normal tibial nerves, freshly transplanted nerves, and nerves stored in Wisconsin/Belzer or Collins solution for 24 or 72 h at 4°C and transplanted. Stored and transplanted segments were processed for morphologic and morphometric analysis. The cross-sections of segments stored in Wisconsin/Belzer and Collins solution presented aspects similar to that of normal nerves. The density of large-caliber myelinated axons was higher in grafts stored in Wisconsin/Belzer solution than in those preserved in Collins solution. But the density of myelinated axons regenerated through these grafts was around 80% to that registered in the fresh and Wisconsin/Belzer preserved grafts. Moreover, no significant differences in the morphometric parameters were observed between groups. Our data confirm the efficacy of Wisconsin/Belzer to nerve graft preservation and stimulate more detailed physiological, biochemical and molecular studies to rationalize the employment of less expensive and handful storage solutions for short term preservation of peripheral nerve grafts.
Editor: 
Rights: aberto
Identifier DOI: 
Address: http://www.scopus.com/inward/record.url?eid=2-s2.0-36448980293&partnerID=40&md5=5fb094951e480573fec0aef6b170862e
Date Issue: 2007
Appears in Collections:Unicamp - Artigos e Outros Documentos

Files in This Item:
File Description SizeFormat 
2-s2.0-36448980293.pdf2.53 MBAdobe PDFView/Open


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.