Please use this identifier to cite or link to this item:
|Type:||Artigo de periódico|
|Title:||Efficient Heck Arylations Of Cyclic And Acyclic Acrylate Derivatives Using Arenediazonium Tetrafluoroborates. A New Synthesis Of The Antidepressant Drug (±)-paroxetine|
|Abstract:||The Heck arylation of acyclic- and cyclic-substituted acrylates using several arenediazonium tetrafluoroborates was investigated. Arylations were carried out under aerobic, ligand-free conditions to provide the corresponding substituted acrylates in moderate to high isolated yields. Heck arylations were usually completed in less than 2 h in refluxing methanol. The aza-endocyclic acrylate derivative 11a was converted into the antidepressant drug (±)-paroxetine in a concise new route in good overall yield. © 2006 American Chemical Society.|
|Appears in Collections:||Unicamp - Artigos e Outros Documentos|
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.