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Type: Artigo de periódico
Title: Synthesis, Characterization And "in Vitro" Degradation Of Plla [síntese, Caracterização E Degradação "in Vitro" Do Poli(l-ácido Láctico)]
Author: Motta A.C.
Duek E.A.R.
Abstract: The study and application of bioreabsorbable polyesters to repair damaged tissues is a promising research area. Poly(L-lactic acid), PLLA, is the most important bioreabsorbable polyester due to it excellent biocompatibility and bioreabsorption. The aim of this work was to synthesize, characterize and evaluate the in vitro degradation process of PLLA membranes. The polymer was synthesized by ring opening of the cyclic diester of lactic acid using as catalyst Sn(Oct) 2. PLLA presented high values of molar mass (M̄ w around 105 g/mol) and its chemical structure was confirmed by RMN 1H, 13C and IR. The thermal properties of PLLA were studied by DSC, from which a high cristallinity degree was observed consistent with the literature. The in vitro degradation of PLLA membranes demonstrated that the crystallinity degree increased with increasing degradation times.
Rights: aberto
Identifier DOI: 
Date Issue: 2006
Appears in Collections:Unicamp - Artigos e Outros Documentos

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