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Type: Artigo de periódico
Title: Multilocular Cystic Renal Cell Carcinoma: A Report Of 45 Cases Of A Kidney Tumor Of Low Malignant Potential
Author: Suzigan S.
Lopez-Beltran A.
Montironi R.
Drut R.
Romero A.
Hayashi T.
Gentili A.L.C.
Fonseca P.S.P.
DeTorres I.
Billis A.
Japp L.C.
Bollito E.
Algaba F.
Requena-Tapias M.J.
Abstract: The 2004 World Health Organization (WHO) classification of kidney tumors recognizes multilocular cystic renal cell carcinoma (MCRCC) as a rare variant of clear cell renal cell carcinoma with a good prognosis. Available information on its clinical significance is limited. The study cohort included 45 MCRCC cases classified according to 2004 WHO criteria obtained through a multi-institutional international search. Most patients had unilateral MCRCC with no side predominance that was found incidentally; 62% were men, but women had tumors at an earlier age (P = .385). MCRCC occurred slightly more often in men than in women (1.7:1). At diagnosis, 82% of patients had stage T1 and 16%, stage 72; 1 patient had stage T3. The Fuhrman grade was 1 (62%) or 2 (38%), with smaller tumors (≤4 cm) most likely Fuhrman grade 1 (P = .911). All 45 patients were alive with no evidence of disease at mean follow-up of 66.1 months, confirming an extremely good prognosis after surgery and a 5-year disease-specific survival rate of 100%. To rename this tumor as multilocular cystic renal cell neoplasm of low malignant potential might help urologists approach the patients conservatively. © American Society for Clinical Pathology.
Rights: fechado
Identifier DOI: 10.1309/AH6F-C77P-YR2V-6YAY
Date Issue: 2006
Appears in Collections:Unicamp - Artigos e Outros Documentos

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