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Type: Artigo de periódico
Title: Is Neurocysticercosis The Main Cause Of Epilepsy In Developing Countries?
Author: Nascimento E Silva R.M.
Kobayashi E.
Cendes F.
Li L.M.
Abstract: We conducted a bibliographic search on Internet using the PubMed site combining the terms neurocysticercosis, epilepsy and calcifications covering the last 20-years period from March 2001 to evaluate previously published studies regarding the causal relationship between neurocysticercosis calcifications (NC) and epilepsy. We reviewed the abstracts and selected those articles that presented risk-analyses, i.e., case-control or cohort studies. We used the criteria proposed by the Oxford Center for Evidence Based Medicine to classify the studies into levels of evidence of risk. Sixteen out of the 174 abstracts were initially selected for a systematic analysis, which showed that most of them (9/16) were case report studies. Five adequate case-control studies were found, which allowed the approach of a cause-effect relationship between NC and epilepsy. We did not find any cohort or randomized study. The analyses show that there are no sufficient data from case-control studies in literature to conclude about the correlation between NC and the development of epilepsy. This is probably due to methodological difficulties and different individual response to the presence of calcifications.
Rights: aberto
Identifier DOI: 
Date Issue: 2003
Appears in Collections:Unicamp - Artigos e Outros Documentos

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