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Type: Artigo de periódico
Title: Simple Fluorescent Pcr Method For Detection Of Large Deletions In The β-globin Gene Cluster
Author: De Andrade T.G.
Saad S.T.O.
Sonati M.D.F.
Costa F.F.
Abstract: We developed a semi-automated approach to detect large deletions in the β-globin gene cluster, based on the quantitative differences in the amplifications of samples by a fluorescent PCR. With this strategy, we were able to detect the presence of HPFH-2 in an African-Brazilian subject, confirmed by sequencing analysis. Differently from other PCR strategies, GAP-PCR for example, it has the potential to identify new deletions. © 2003 Wiley-Liss, Inc.
Rights: fechado
Identifier DOI: 10.1002/ajh.10291
Date Issue: 2003
Appears in Collections:Unicamp - Artigos e Outros Documentos

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