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Type: Artigo de periódico
Title: Use Of Corticosteroids After Esophageal Dilations On Patients With Corrosive Stenosis: Prospective, Randomized And Double-blind Study [o Uso De Corticoesteróides Após Dilata O Esofágica Em Pacientes Portadores De Estenose Por Substâncias Corrosivas: Estudo Prospectivo, Randomizado E Duplo-cego.]
Author: Camargo M.A.
Lopes L.R.
Grangeia T.A.
Andreollo N.A.
Brandalise N.A.
Abstract: OBJECTIVE: To determine triancinolone intralesional injections effects in association with esophageal dilations in corrosive stenosis cases, by means of a double-blind and randomized study. METHOD: Fourteen adults patients (6 men and 8 women) with severe esophageal corrosive stenosis were randomized in two groups: Group A: treated by esophageal dilations and posterior triancinolone 10 mg/ml intralesional injection; Group B: treated by esophageal injections and posterior saline solution 0,9% injection (placebo). New applications were made based on the patient symptomatology. It had been analysed dilation frequency, obtained diameters and dysphagia before and after the research, for 12 months. RESULTS: Eleven patients had ingested sodium hydroxide, two had ingested ammoniac and one had taken muriatic acid. There was no statistic difference (p > 0.05) in dilation frequency and dysphagia between the groups. However, an improvement in obtained diameter was observed in the corticosteroids group in comparison with control group (p < 0.05). By comparing groups before and after steroids, the final results were very favorable in group A CONCLUSION: Multiple intralesional injections of triancinolone hexacetonide 10 mg/ml in association with esophageal dilations increase obtained diameters in succeeding sessions.
Rights: fechado
Identifier DOI: 
Date Issue: 2003
Appears in Collections:Unicamp - Artigos e Outros Documentos

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