Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/101676
Type: Artigo de periódico
Title: Evaluation Of Argyrophilic Nucleolar Organizer Regions In Oral Tumor Progression
Author: Spolidorio L.C.
Neves K.A.
Soares C.P.
Spolidorio D.M.P.
Basso M.F.M.
Malavazzi I.
Almeida O.P.
Abstract: The aim of this study was to compare the presence of nucleolar organizer regions (NORs) in normal oral mucosa, dysplasia and microinvasive carcinoma. All histological specimens were reviewed according to the modified classification and staging system for oral leukoplakia described by van-der-Waal et al. [Oral Oncol. 36 (2000) 264]. NOR quantification was performed with an image analyzer after staining by the argyrophilic nucleolar region technique. The morphometric results were statistically different for normal mucosa, dysplasia and microinvasive carcinoma. It was concluded that an increase of NOR activity follows the disease progression and may reflect the degree of cellular proliferation and malignancy. © 2002 Elsevier Science Ltd. All rights reserved.
Editor: 
Rights: fechado
Identifier DOI: 10.1016/S0968-4328(02)00031-8
Address: http://www.scopus.com/inward/record.url?eid=2-s2.0-0036446038&partnerID=40&md5=6c58976e02547ff709988b141e84f710
Date Issue: 2002
Appears in Collections:Unicamp - Artigos e Outros Documentos

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