Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/101537
Type: Artigo de periódico
Title: Dorzolamide X Apraclonidine In The Prevention Of The Intraocular Pressure Spike After Nd:yag Laser Posterior Capsulotomy
Author: Arieta C.E.L.
Amaral M.S.
Matuda E.
Crosta C.
De Carvalho Moreira Filho D.
Jose N.K.
Abstract: Objective. To evaluate the efficacy of dorzolamide compared to apraclonidine, in the prevention of the intra-ocular pressure (IOP) spike after Nd:YAG laser posterior capsulotomy. Site. Department of Ophthalmology, State University of Campinas (UNICAMP) General Hospital, Campinas, São Paulo, Brazil. Methods. In a double masked prospective clinical trial, 217 eyes from 217 patients were randomly assigned to receive either dorzolamide 2 h before and placebo l h before Nd:YAG laser capsulotomy or placebo 2 h before and apraclonidine 1 h before the procedure. Inclusion criteria were secondary cataracts with reduction in best corrected visual acuity (BCVA < 20/40), absence of manifest or suspected glaucoma and no known hypersensitivity to the study drugs. IOP was measured 2 h and 1 h before applying the laser, and 1 h, 2 h, 3 h and 7 days after. Results. There were no statistically significant differences between the two groups regarding the IOP 2 h and 1 h before the procedure, and 1 h, 2 h, 3 h and 7 days after the laser treatment (p values, respectively: 0.077, 0.21, 0.085, 0.36, and 0.60). Conclusion. The results of this study suggest that dorzolamide is as safe and effective as apraclonidine in the prevention of the IOP elevation after Nd:YAG laser posterior capsulotomy. Synopsis. The efficacy of dorzolamide was compared to apraclonidine in the prevention of the intraocular pressure spike after Nd:YAG laser posterior capsulotomy in 217 patients and the results were similar with both drugs.
Editor: 
Rights: fechado
Identifier DOI: 10.1076/ceyr.25.4.237.13484
Address: http://www.scopus.com/inward/record.url?eid=2-s2.0-0036820713&partnerID=40&md5=dc596b7499dd2a14775da3f75b7de914
Date Issue: 2002
Appears in Collections:Unicamp - Artigos e Outros Documentos

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