Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/101179
Type: Artigo de periódico
Title: Percutaneous Renal Graft Biopsy: A Clinical, Laboratory And Pathological Analysis.
Author: Mazzali M.
Ribeiro-Alves M.A.
Alves Filho G.
Abstract: CONTEXT: Renal allograft biopsies have been used as a good method for monitoring the evolution of kidney transplants for at least 20 years. Histological analysis permits differential diagnosis of the causes of allograft dysfunction to be made. OBJECTIVES: To correlate the data of urinalysis and serum creatinine with histological diagnosis of renal graft in a group of renal transplant patients. DESIGN: Accuracy study, retrospective analysis. SETTING: A university terciary referral center. SAMPLE: 339 percutaneous allograft biopsies obtained from 153 patients. Blood and urine samples were obtained before the graft biopsy. MAIN MEASUREMENTS: Laboratory evaluation and hystological analysis (light microscopy, immunofluorescent electronic microscopy). RESULTS: Most of the biopsies (58.9%) were performed during the first month post-transplant. An increase in serum creatinine was associated with acute tubular and/or cortical necrosis. Proteinuria and normal serum creatinine were associated with glomerular lesions. Non-nephrotic range proteinuria and an increase in serum creatinine were associated with chronic rejection. CONCLUSION: Evaluation of serum creatinine and urinalysis can be useful in suggesting the histological graft diagnosis.
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Rights: aberto
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Address: http://www.scopus.com/inward/record.url?eid=2-s2.0-0033522021&partnerID=40&md5=18503c01ed9c33f7a60bf6c3308fc4a9
Date Issue: 1999
Appears in Collections:Unicamp - Artigos e Outros Documentos

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