Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/100500
Type: Artigo
Title: Blood glucose determination in normal and alloxan-diabetic rats after administration of local anesthetics containing vasoconstrictors
Author: Esmerino, L. A.
Ranali, J.
Rodrigues Jr., A. L.
Abstract: Normal and alloxan-diabetic rats were injected submucously in the posterior region of the upper jaw with bupivacaine (1.28 mg/kg) containing adrenaline (0.0012 mg/kg), or lignocaine (5.14 mg/kg) containing noradrenaline (0.005 mg/kg). Blood glucose was determined at zero (before administration), 0.5, 1, 2, 3 and 4 hours after the administration of the anesthetics. Statistical analysis (ANOVA and Tukey's test, P < 0.05) showed significant differences between treatments at 1 hour in normal rats. Bupivacaine with adrenaline induced a significantly greater blood glucose level than lignocaine with noradrenaline. The effect was significant but of short duration. In alloxan-diabetic rats, anesthetics containing adrenaline or noradrenaline did not induce increased blood glucose levels.
Normal and alloxan-diabetic rats were injected submucously in the posterior region of the upper jaw with bupivacaine (1.28 mg/kg) containing adrenaline (0.0012 mg/kg), or lignocaine (5.14 mg/kg) containing noradrenaline (0.005 mg/kg). Blood glucose was determined at zero (before administration), 0.5, 1, 2, 3 and 4 hours after the administration of the anesthetics. Statistical analysis (ANOVA and Tukey's test, P < 0.05) showed significant differences between treatments at 1 hour in normal rats. Bupivacaine with adrenaline induced a significantly greater blood glucose level than lignocaine with noradrenaline. The effect was significant but of short duration. In alloxan-diabetic rats, anesthetics containing adrenaline or noradrenaline did not induce increased blood glucose levels
Subject: Catecolaminas
Anestésicos locais
Country: Brasil
Editor: USP/Fundação Odontológica de Ribeirão Preto
Citation: Brazilian Dental Journal. , v. 9, n. 1, p. 33 - 37, 1998.
Rights: aberto
Address: http://www.forp.usp.br/bdj/Bdj9(1)/t0591/t0591.html
Date Issue: 1998
Appears in Collections:FOP - Artigos e Outros Documentos

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