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Type: Artigo de evento
Title: Acetylsalicylic Acid Determination In Pharmaceutical Samples By Fia-potentiometry Using A Salicylate-sensitive Tubular Electrode With An Ethylene-vinyl Acetate Membrane
Author: Rover Jr. L.
Garcia C.A.B.
Neto G.D.O.
Kubota L.T.
Galembeck F.
Abstract: The construction of a salicylate-sensitive tubular potentiometric electrode for flow injection analysis (FIA) is described, in which an ethylene-vinyl acetate (EVA) copolymeric membrane, 40% in vinyl acetate, is applied directly onto a conducting support consisting of a mixture of an epoxy resin and graphite. The tubular salicylate ion-selective electrode is based on tricaprylyl-trimethyl-ammonium (Aliquat(TM)) salicylate as the ion-exchanger, supported on the polymeric matrix without plasticizer solvent. The tubular electrode showed a response of 58.3mV per concentration decade within the 5.0x10-3-5.0x10-1moll-1 salicylate range in 0.1moll-1 Tris-HCl buffer (pH=7.5). Iodide is the main analytical interferent; the electrode response time was 5s at 25°C. Determinations of acetylsalicylic acid in tablet samples by the proposed method exhibit relative errors lower than 2%, when compared with a spectrophotometric method. The useful lifetime of the tubular sensor is longer than 3 months. Copyright (C) 1998 Elsevier Science B.V.
Rights: fechado
Identifier DOI: 10.1016/S0003-2670(97)00723-X
Date Issue: 1998
Appears in Collections:Unicamp - Artigos e Outros Documentos

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