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Type: Artigo de periódico
Title: Systemic Lupus Erythematosus And Central Nervous System Infection: Retrospective Study Of 350 Cases [lupus Eritematoso Sistemico E Infeccao No Sistema Nervoso Central: Estudo Retrospectivo De 350 Casos]
Author: Costallat L.T.L.
Yamada R.M.
De Paula Leite Cury Lia C.
Samara A.M.
Abstract: The goal of this report on SLE is to show the incidence of CNS infection in this disease and its clinical profile, as well as the patient susceptibility to that complication. The authors studied a total of 350 patients, 16 of them with CNS infection. They were evaluated by clinical, radiological and laboratory data. Twelve had meningitis, two neurotoxoplasmosis, one neurocryptococosis and one bacterial abscess. The main symptoms were fever, headache, nape stiffness, vomits, seizures and papiledema. Half of the patients with CNS infection were on steroids alone and the remaining patients were on steroids associated with remissive disease modifying drugs. 75% of patients with CNS infection had some kind of SLE activity concomitant to infection, and 50% (8 cases) had a poor prognosis, represented by death. CNS infection is a relativity rare complication of SLE, with high mortality. Early clinical suspicion, diagnosis, and therapeutic intervention are important for better prognosis.
Rights: fechado
Identifier DOI: 
Date Issue: 1997
Appears in Collections:Unicamp - Artigos e Outros Documentos

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