Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/100003
Type: Artigo de periódico
Title: Qsar Based On Biological Microcalorimetry. Iii Interaction Of M-alcoxyphenols And P-hydroxybenzoates With Escherichia Coli [estudos De Qsar Baseados Em Dados De Atividade Biológica Obtidos Por Microcalorimetria. Iii Interaçåo De M-alcoxifenóis E P-hidroxibenzoatos De Alquila Com Escherichia Coli]
Author: Volpe P.L.O.
Montanari C.A.
Abstract: QSAR studies based on flow microcalorimetric bioassay data for interaction of homologous series of m-alkoxyphenols and p-hydroxybenzoates with E. coli cells were carried out applying factorial design. Results for both series showed a linear relationship between log(dose)max and log Po/w. Analysis of these data allows the identification of contributions toward the derived bioactivity from the parent structures (the molecule minus n-CH2 groups present in the side-chain) and the lipophilic groups, CH2. These results are discussed with respect to drug quantitative structure-relationship.
Editor: 
Rights: aberto
Identifier DOI: 
Address: http://www.scopus.com/inward/record.url?eid=2-s2.0-0008120049&partnerID=40&md5=f9de9279e75f948f539b3f8f7e63fdd7
Date Issue: 1997
Appears in Collections:Unicamp - Artigos e Outros Documentos

Files in This Item:
File Description SizeFormat 
2-s2.0-0008120049.pdf55.12 kBAdobe PDFView/Open


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.