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dc.contributor.CRUESPUniversidade Estadual de Campinaspt_BR
dc.typeArtigo de periódicopt_BR
dc.titleEcotoxicological Evaluation of Poly(epsilon-Caprolactone) Nanocapsules Containing Triazine Herbicidespt_BR
dc.contributor.authorClemente, Zpt_BR
dc.contributor.authorGrillo, Rpt_BR
dc.contributor.authorJonsson, Mpt_BR
dc.contributor.authorSantos, NZPpt_BR
dc.contributor.authorFeitosa, LOpt_BR
dc.contributor.authorLima, Rpt_BR
dc.contributor.authorFraceto, LFpt_BR
unicamp.authorClemente, Z. Jonsson, M. Embrapa Environm, BR-13820000 Jaguariuna, SP, Brazilpt_BR
unicamp.authorClemente, Z. Grillo, R. Fraceto, L. F. Univ Estadual Campinas, Inst Biol, Dept Biochem, BR-13083970 Campinas, SP, Brazilpt_BR
unicamp.authorGrillo, R. Fraceto, L. F. UNESP, Dept Environm Engn, BR-18087180 Campus Sorocaba, SP, Brazilpt_BR
unicamp.authorSantos, N. Z. P. Feitosa, L. O. Lima, R. Univ Sorocaba, Dept Biotechnol, BR-18023000 Sorocaba, SP, Brazilpt_BR
dc.subjectEnvironmental Chemistrypt_BR
dc.subjectTriazine Herbicidespt_BR
dc.subjectPolymeric Nanoparticlespt_BR
dc.subjectGenotoxicitypt_BR
dc.subjectEcotoxicologypt_BR
dc.subject.wosControlled-releasept_BR
dc.subject.wosAlginate/chitosan Nanoparticlespt_BR
dc.subject.wosBeta-cyclodextrinpt_BR
dc.subject.wosSoil Sorptionpt_BR
dc.subject.wosIn-vitropt_BR
dc.subject.wosAtrazinept_BR
dc.subject.wosGenotoxicitypt_BR
dc.subject.wosMetolachlorpt_BR
dc.subject.wosNanospherespt_BR
dc.subject.wosClomazonept_BR
dc.description.abstractThe triazine class of herbicides includes the compounds ametryn, atrazine, and simazine, which are used to control weeds in plantations of crops such as maize, sorghum, and sugar cane. Despite their acceptance in agriculture, these herbicides can be dangerous to the environment, depending on their toxicity, the degree of contamination, and the duration of exposure. Controlled release systems are increasingly used to mitigate problems of toxicity and minimize environmental impacts, and can also increase herbicide efficiency. The objective of this work was to prepare poly(epsilon-caprolactone) nanocapsules containing ametryn and atrazine, and evaluate their toxicity to aquatic organisms as well as in cytogenetic tests employing human lymphocyte cultures. The PCL nanocapsules were prepared according to the interfacial deposition of pre-formed polymer method. Ecotoxicological assays were performed with the alga Pseudokirchneriella subcapitata and the microcrustacean Daphnia similis. The cytogenetic tests consisted of observing mitotic index alterations after exposing lymphocyte cell cultures to different formulations. Encapsulation of the herbicides in the nanocapsules resulted in lower toxicity to the alga and higher toxicity to the microcrustacean, compared to the herbicides alone. The cytogenetic tests showed that formulations of nanocapsules containing the herbicides were less toxic than the herbicides alone. The findings indicate the potential of the nanocapsule formulations in agricultural applications, where they could help to reduce the quantities of herbicides used as well as impacts on the environment and human health.pt
dc.relation.ispartofJournal Of Nanoscience And Nanotechnologypt_BR
dc.relation.ispartofabbreviationJ. Nanosci. Nanotechnol.pt_BR
dc.publisher.cityValenciapt_BR
dc.publisher.countryEUApt_BR
dc.publisherAmer Scientific Publisherspt_BR
dc.date.issued2014pt_BR
dc.date.monthofcirculationJULpt_BR
dc.identifier.citationJournal Of Nanoscience And Nanotechnology. Amer Scientific Publishers, v. 14, n. 7, n. 4911, n. 4917, 2014.pt_BR
dc.language.isoenpt_BR
dc.description.volume14pt_BR
dc.description.issuenumber7pt_BR
dc.description.firstpage4911pt_BR
dc.description.lastpage4917pt_BR
dc.rightsfechadopt_BR
dc.sourceWeb of Sciencept_BR
unicamp.cruespUNESPpt_BR
dc.identifier.issn1533-4880pt_BR
dc.identifier.eissn1533-4899pt_BR
dc.identifier.wosidWOS:000332926400021pt_BR
dc.identifier.doi10.1166/jnn.2014.8681pt_BR
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)pt_BR
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)pt_BR
dc.description.sponsorshipFundação para o Desenvolvimento da UNESP (FUNDUNESP)pt_BR
dc.description.sponsorship1Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)pt_BR
dc.description.sponsorship1Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)pt_BR
dc.date.available2014-07-30T17:05:11Z
dc.date.available2015-11-26T17:42:58Z-
dc.date.accessioned2014-07-30T17:05:11Z
dc.date.accessioned2015-11-26T17:42:58Z-
dc.description.provenanceMade available in DSpace on 2014-07-30T17:05:11Z (GMT). No. of bitstreams: 0 Previous issue date: 2014en
dc.description.provenanceMade available in DSpace on 2015-11-26T17:42:58Z (GMT). No. of bitstreams: 0 Previous issue date: 2014en
dc.identifier.urihttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/63662
dc.identifier.urihttp://repositorio.unicamp.br/jspui/handle/REPOSIP/63662-
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