Please use this identifier to cite or link to this item:
Type: Artigo de periódico
Title: Amygdalae calcifications associated with disease duration in lipoid proteinosis
Author: Appenzeller, S
Chaloult, E
Velho, P
de Souza, EM
Araujo, VZ
Cendes, F
Li, LM
Abstract: Objectives. To describe imaging findings of central nervous system involvement in patients with lipoid proteinosis. Methods. Patients with lipoid proteinosis followed in the dermatology and neurology departments of the State University of Campinas between 2002 and 2004 were evaluated using high-resolution MRI and computerized tomography (CT). Results. We reviewed the charts of three patients (two women) with lipoid proteinosis with, ages ranging from 5 to 44 years. Symptomatic disease duration ranged from 2 to 39 years. MRI scans showed hypointense signal in FLAIR and T2 images in the amygdalae in two of three patients. Brain CT scans from two patients showed that MRI findings were calcifications. The calcification was more evident in patients with longer disease duration. Epilepsy was identified in one patient with longer disease duration. No other epileptogenic lesion was identified on MRI in this patient. Conclusion. Lipoid proteinosis is associated with bilateral amygdalae calcification. These findings were more evident in patients with longer disease duration. Epilepsy, when present, may be related to these calcifications. Patients with lipoid proteinosis should be followed with MRI/CT in order to identify these abnormalities.
Subject: neuroimaging
amygdala calcifications
lipoid proteinosis
Urbach-Wiethe disease
Country: Inglaterra
Editor: Blackwell Publishing
Citation: Journal Of Neuroimaging. Blackwell Publishing, v. 16, n. 2, n. 154, n. 156, 2006.
Rights: fechado
Identifier DOI: 10.1111/j.1552-6569.2005.00018.x
Date Issue: 2006
Appears in Collections:Unicamp - Artigos e Outros Documentos

Files in This Item:
File Description SizeFormat 
WOS000236453800009.pdf225.97 kBAdobe PDFView/Open

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.