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dc.contributor.CRUESPUniversidade Estadual de Campinaspt_BR
dc.typeArtigo de periódicopt_BR
dc.titleAction of Coriandrum sativum L. Essential Oil upon Oral Candida albicans Biofilm Formationpt_BR
dc.contributor.authorFurletti, VFpt_BR
dc.contributor.authorTeixeira, IPpt_BR
dc.contributor.authorObando-Pereda, Gpt_BR
dc.contributor.authorMardegan, RCpt_BR
dc.contributor.authorSartoratto, Apt_BR
dc.contributor.authorFigueira, GMpt_BR
dc.contributor.authorDuarte, RMTpt_BR
dc.contributor.authorRehder, VLGpt_BR
dc.contributor.authorDuarte, MCTpt_BR
dc.contributor.authorHofling, JFpt_BR
unicamp.authorFurletti, V. F. Teixeira, I. P. Obando-Pereda, G. Mardegan, R. C. Hoefling, J. F. Univ Campinas UNICAMP, Dent Sch Piracicaba, Dept Microbiol & Immunol, BR-13414903 Piracicaba, SP, Brazilpt_BR
unicamp.authorFurletti, V. F. Teixeira, I. P. Obando-Pereda, G. Mardegan, R. C. Sartoratto, A. Figueira, G. M. Duarte, R. M. T. Rehder, V. L. G. Duarte, M. C. T. Univ Campinas UNICAMP, Res Ctr Chem Biol & Agr, BR-13083970 Campinas, SP, Brazilpt_BR
dc.subject.wosOropharyngeal Candidiasispt_BR
dc.description.abstractThe efficacy of extracts and essential oils from Allium tuberosum, Coriandrum sativum, Cymbopogon martini, Cymbopogon winterianus, and Santolina chamaecyparissus was evaluated against Candida spp. isolates from the oral cavity of patients with periodontal disease. The most active oil was fractionated and tested against C. albicans biofilm formation. The oils were obtained by water-distillation and the extracts were prepared with macerated dried plant material. The Minimal Inhibitory Concentration-MIC was determined by the microdilution method. Chemical characterization of oil constituents was performed using Gas Chromatography and Mass Spectrometry (GC-MS). C. sativum activity oil upon cell and biofilm morphology was evaluated by Scanning Electron Microscopy (SEM). The best activities against planktonic Candida spp. were observed for the essential oil and the grouped F(8-10) fractions from C. sativum. The crude oil also affected the biofilm formation in C. albicans causing a decrease in the biofilm growth. Chemical analysis of the F(8-10) fractions detected as major active compounds, 2-hexen-1-ol, 3-hexen-1-ol and cyclodecane. Standards of these compounds tested grouped provided a stronger activity than the oil suggesting a synergistic action from the major oil constituents. The activity of C. sativum oil demonstrates its potential for a new natural antifungal
dc.relation.ispartofEvidence-based Complementary And Alternative Medicinept_BR
dc.relation.ispartofabbreviationEvid.-based Complement Altern. Med.pt_BR
dc.publisher.cityNew Yorkpt_BR
dc.publisherHindawi Publishing Corporationpt_BR
dc.identifier.citationEvidence-based Complementary And Alternative Medicine. Hindawi Publishing Corporation, n. 1, n. 9, 2011.pt_BR
dc.sourceWeb of Sciencept_BR
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)pt_BR
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)pt_BR
dc.description.sponsorship1Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)pt_BR
dc.description.sponsorship1Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)pt_BR
dc.description.provenanceMade available in DSpace on 2014-07-30T13:43:29Z (GMT). No. of bitstreams: 0 Previous issue date: 2011en
dc.description.provenanceMade available in DSpace on 2015-11-26T16:33:28Z (GMT). No. of bitstreams: 2 WOS000293647400001.pdf: 2091134 bytes, checksum: c5dfea1a78988af9342dba3a2cd11756 (MD5) WOS000293647400001.pdf.txt: 38972 bytes, checksum: 039b7268eccd8062acf84ace942ff046 (MD5) Previous issue date: 2011en
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