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Type: Artigo
Title: Comparative Study Of Chemical Composition And Biological Activity Of Yellow, Green, Brown, And Red Brazilian Propolis
Author: Machado
Christiane Schineider; Mokochinski
Joao Benhur; de Lira
Tatiana Onofre; Evangelista de Oliveira
Fatima de Cassia; Cardoso
Magda Vieira; Ferreira
Roseane Guimaraes; Helena Frankland Sawaya
Alexandra Christine; Ferreira
Antonio Gilberto; Pessoa
Claudia; Cuesta-Rubio
Osmany; Monteiro
Marta Chagas; de Campos
Monica Soares; Torres
Yohandra Reyes
Abstract: The chemical composition and biological activity of a sample of yellow propolis from Mato Grosso do Sul, Brazil (EEP-Y MS), were investigated for the first time and compared with green, brown, and red types of Brazilian propolis and with a sample of yellow propolis from Cuba. Overall, EEP-Y MS had different qualitative chemical profiles, as well as different cytotoxic and antimicrobial activities when compared to the other types of propolis assessed in this study and it is a different chemotype of Brazilian propolis. Absence of phenolic compounds and the presence of mixtures of aliphatic compounds in yellow propolis were determined by analysing H-1-NMR spectra and fifteen terpenes were identified by GC-MS. EEP-Y MS showed cytotoxic activity against human tumour strain OVCAR-8 but was not active against Gram-negative or Gram-positive bacteria. Our results confirm the difficulty of establishing a uniform quality standard for propolis from diverse geographical origins. The most appropriate pharmacological applications of yellow types of propolis must be further investigated.
Editor: Hindawi Publishing Corp
New York
Citation: Evidence-based Complementary And Alternative Medicine. Hindawi Publishing Corp, p. , 2016.
Rights: aberto
Identifier DOI: 10.1155/2016/6057650
Date Issue: 2016
Appears in Collections:Unicamp - Artigos e Outros Documentos

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