Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/241863
Type: Artigo de periódico
Title: Development Of New Uv-vis Spectroscopic Microwave-assisted Method For Determination Of Glucose In Pharmaceutical Samples
Author: Mabood
Fazal; Hussain
Z.; Haq
H.; Arian
M. B.; Boque
R.; Khan
K. M.; Hussain
K.; Jabeen
F.; Hussain
J.; Ahmed
M.; Alharasi
A.; Naureen
Z.; Hussain
H.; Khan
A.; Perveen
S.
Abstract: A new UV-Visible spectroscopic method assisted with microwave for the determination of glucose in pharmaceutical formulations was developed. In this study glucose solutions were oxidized by ammonium molybdate in the presence of microwave energy and reacted with aniline to produce a colored solution. Optimum conditions of the reaction including wavelength, temperature, and pH of the medium and relative concentration ratio of the reactants were investigated. It was found that the optimal wavelength for the reaction is 610 nm, the optimal reaction time is 80 s, the optimal reaction temperature is 160 degrees C, the optimal reaction pH is 4, and the optimal concentration ratio aniline/ammonium molybdate solution was found to be 1:1. The limits of detection and quantification of the method are 0.82 and 2.75 ppm for glucose solution, respectively. The use of microwaves improved the speed of the method while the use of aniline improved the sensitivity of the method by shifting the wavelength. (C) 2015 Elsevier B.V. All rights reserved.
Subject: Blood-glucose
Aniline
Polymerization
Phosphate
Lactate
Oxidase
System
Muscle
Memory
Sugars
Country: OXFORD
Editor: PERGAMON-ELSEVIER SCIENCE LTD
Citation: Development Of New Uv-vis Spectroscopic Microwave-assisted Method For Determination Of Glucose In Pharmaceutical Samples. Pergamon-elsevier Science Ltd, v. 153, p. 212-215 Jan-2016.
Rights: embargo
Identifier DOI: 10.1016/j.saa.2015.08.035
Address: http://www.sciencedirect.com/science/article/pii/S1386142515301931
Date Issue: 2016
Appears in Collections:Unicamp - Artigos e Outros Documentos

Files in This Item:
File SizeFormat 
wos_000365360700029.pdf373.75 kBAdobe PDFView/Open


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.