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|Type:||Artigo de periódico|
|Title:||Epicolactone - Natural Product Isolated from the Sugarcane Endophytic Fungus Epicoccum nigrum|
|Author:||da Silva Araujo, Francisca Diana|
de Lima Favaro, Leia Cecilia
Araujo, Welington Luiz
de Oliveira, Fabio Lazzarotto
Marsaioli, Anita Jocelyne
|Abstract:||The endophytic fungus Epicoccum nigrum was isolated from sugarcane and the bioguided fractionation of the ethyl acetate extract led to the isolation of epicolactone, mellein, and 4,5-dimethylresorcinol. Characterization of epicolactone by MS, NMR and X-ray crystallography revealed a new natural product with an unusual carbon skeleton. The production of this secondary metabolite decreased in mutants of Epicoccum nigrum transformed by Agrobacterium tumefaciens. Additionally, these mutants produced 4-hydroxymellein.|
|Citation:||European Journal of Organic Chemistry. Wiley-Blackwell, n.27, p.5225-5230, 2012|
|Appears in Collections:||IQ - Artigos e Outros Documentos|
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