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Type: Artigo de periódico
Title: Epicolactone - Natural Product Isolated from the Sugarcane Endophytic Fungus Epicoccum nigrum
Author: da Silva Araujo, Francisca Diana
de Lima Favaro, Leia Cecilia
Araujo, Welington Luiz
de Oliveira, Fabio Lazzarotto
Aparicio, Ricardo
Marsaioli, Anita Jocelyne
Abstract: The endophytic fungus Epicoccum nigrum was isolated from sugarcane and the bioguided fractionation of the ethyl acetate extract led to the isolation of epicolactone, mellein, and 4,5-dimethylresorcinol. Characterization of epicolactone by MS, NMR and X-ray crystallography revealed a new natural product with an unusual carbon skeleton. The production of this secondary metabolite decreased in mutants of Epicoccum nigrum transformed by Agrobacterium tumefaciens. Additionally, these mutants produced 4-hydroxymellein.
Subject: Natural products
Bioorganic chemistry
Epicoccum nigrum
Editor: Wiley-Blackwell
Citation: European Journal of Organic Chemistry. Wiley-Blackwell, n.27, p.5225-5230, 2012
Rights: fechado
Identifier DOI: 10.1002/ejoc.201200757
Date Issue: 2012
Appears in Collections:IQ - Artigos e Outros Documentos

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