Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/201338
Type: Artigo de periódico
Title: Intracluster Correlation Coefficients For The Brazilian Multicenter Study On Preterm Birth (emip): Methodological And Practical Implications.
Author: Lajos, Giuliane J
Haddad, Samira M
Tedesco, Ricardo P
Passini, Renato
Dias, Tabata Z
Nomura, Marcelo L
Rheder, Patrícia M
Sousa, Maria H
Cecatti, Jose G
Abstract: Cluster-based studies in health research are increasing. An important characteristic of such studies is the presence of intracluster correlation, typically quantified by the intracluster correlation coefficient (ICC), that indicate the proportion of data variability that is explained by the way of clustering. The purpose of this manuscript was to evaluate ICC of variables studied in the Brazilian Multicenter Study on Preterm Birth. This was a multicenter cross-sectional study on preterm births involving 20 referral hospitals in different regions of Brazil plus a nested case-control study to assess associated factors with spontaneous preterm births. Estimated prevalence rates or means, ICC with 95% confidence intervals, design effects and mean cluster sizes were presented for more than 250 maternal and newborn variables. Overall, 5296 cases were included in the study (4,150 preterm births and 1,146 term births). ICC ranged from <0.001 to 0.965, with a median of 0.028. For descriptive characteristics (socio-demographic, obstetric history and perinatal outcomes) the median ICC was 0.014, for newborn outcomes the median ICC was 0.041 and for process variables (clinical management and delivery), it was 0.102. ICC was <0.1 in 78.4% of the variables and <0.3 for approximately 95% of them. Most of ICC >0.3 was found in some clinical management aspects well defined in literature such as use of corticosteroids, indicating there was homogeneity in clusters for these variables. Clusters selected for Brazilian Multicenter Study on Preterm Birth had mainly heterogeneous findings and these results can help researchers estimate the required sample size for future studies on maternal and perinatal health.
Subject: Brazil
Case-control Studies
Cluster Analysis
Cross-sectional Studies
Data Interpretation, Statistical
Demography
Female
Fetal Membranes, Premature Rupture
Humans
Infant Mortality
Infant, Newborn
Pregnancy
Pregnancy Outcome
Premature Birth
Questionnaires
Research Design
Citation: Bmc Medical Research Methodology. v. 14, p. 54, 2014.
Rights: fechado
Identifier DOI: 10.1186/1471-2288-14-54
Address: http://www.ncbi.nlm.nih.gov/pubmed/24755392
Date Issue: 2014
Appears in Collections:Unicamp - Artigos e Outros Documentos

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