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dc.contributor.CRUESPUNIVERSIDADE DE ESTADUAL DE CAMPINASpt_BR
dc.typeArtigo de periódicopt_BR
dc.title[characterization Of Multidrug-resistant Tuberculosis During Pregnancy In Campinas, State Of São Paulo, Brazil, From 1995 To 2007].pt_BR
dc.contributor.authorOliveira, Helenice Bosco dept_BR
dc.contributor.authorMateus, Silvia Helena Rondinapt_BR
unicamp.authorHelenice Bosco de Oliveira, Departamento de Medicina Preventiva e Social, Universidade Estadual de Campinas, Campinas, Brazil. helenice@unicamp.brpt_BR
unicamp.author.externalSilvia Helena Rondina Mateus,pt
dc.subjectAdolescentpt_BR
dc.subjectAdultpt_BR
dc.subjectAntitubercular Agentspt_BR
dc.subjectBrazilpt_BR
dc.subjectCohort Studiespt_BR
dc.subjectFemalept_BR
dc.subjectHumanspt_BR
dc.subjectInfant, Newbornpt_BR
dc.subjectInfectious Disease Transmission, Verticalpt_BR
dc.subjectPregnancypt_BR
dc.subjectPregnancy Complications, Infectiouspt_BR
dc.subjectRetrospective Studiespt_BR
dc.subjectTreatment Outcomept_BR
dc.subjectTuberculosis, Multidrug-resistantpt_BR
dc.subjectTuberculosis, Pulmonarypt_BR
dc.subjectYoung Adultpt_BR
dc.description.abstractThere was a follow-up of pregnant women treated for multidrug-resistance tuberculosis (MDR-TB) during pregnancy in Campinas, State of São Paulo, Brazil, from 1995 to 2007. In a retrospective study, patients with tuberculosis who were resistant to at least isoniazid and rifampicin and had pregnancy at any time during the treatment were included. The cases were individually treated, considering drug susceptibility test results and patients' prior treatments. Seven cases presented resistance to two or more drugs. Three were already pregnant before the beginning of the treatment, and four conceived after. Two were with AIDS; one died, and the therapeutic program in the other one failed. All showed advanced tuberculosis with acute radiological findings, and the median sputum conversion time for five patients was four months. Two patients were cured. Two newborn babies were infected with HIV by their mothers. The outcome was unsatisfactory, and direct supervision is imperative in MDR-TB during pregnancy. The family planning program should be strongly recommended.en
dc.relation.ispartofRevista Da Sociedade Brasileira De Medicina Tropicalpt_BR
dc.relation.ispartofabbreviationRev. Soc. Bras. Med. Trop.pt_BR
dc.date.issued2011-Octpt_BR
dc.identifier.citationRevista Da Sociedade Brasileira De Medicina Tropical. v. 44, n. 5, p. 627-30, 2011-Oct.pt_BR
dc.language.isoporpt_BR
dc.description.volume44pt_BR
dc.description.firstpage627-30pt_BR
dc.rightsabertopt_BR
dc.sourcePubMedpt_BR
dc.identifier.issn1678-9849pt_BR
dc.identifier.urlhttp://www.ncbi.nlm.nih.gov/pubmed/22031080pt_BR
dc.date.available2015-11-27T13:21:59Z-
dc.date.accessioned2015-11-27T13:21:59Z-
dc.description.provenanceMade available in DSpace on 2015-11-27T13:21:59Z (GMT). No. of bitstreams: 1 pmed_22031080.pdf: 573695 bytes, checksum: 7fb5364bd4dee46258f1f53d41998429 (MD5) Previous issue date: 2011en
dc.identifier.urihttp://repositorio.unicamp.br/jspui/handle/REPOSIP/199672-
dc.identifier.idPubmed22031080pt_BR
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