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dc.contributor.CRUESPUNIVERSIDADE DE ESTADUAL DE CAMPINASpt_BR
dc.typeArtigo de periódicopt_BR
dc.titleMr Imaging Texture Analysis Of The Corpus Callosum And Thalamus In Amnestic Mild Cognitive Impairment And Mild Alzheimer Disease.pt_BR
dc.contributor.authorde Oliveira, M Spt_BR
dc.contributor.authorBalthazar, M L Fpt_BR
dc.contributor.authorD'Abreu, Apt_BR
dc.contributor.authorYasuda, C Lpt_BR
dc.contributor.authorDamasceno, B Ppt_BR
dc.contributor.authorCendes, Fpt_BR
dc.contributor.authorCastellano, Gpt_BR
unicamp.authorM S de Oliveira, Department of Cosmic Rays and Chronology, Institute of Physics Gleb Wataghin, University of Campinas, São Paulo, Brazil. marciaso@ifi.unicamp.brpt_BR
unicamp.author.externalM L F Balthazar,pt
unicamp.author.externalA D'Abreu,pt
unicamp.author.externalC L Yasuda,pt
unicamp.author.externalB P Damasceno,pt
unicamp.author.externalF Cendes,pt
unicamp.author.externalG Castellano,pt
dc.subjectAgedpt_BR
dc.subjectAged, 80 And Overpt_BR
dc.subjectAlgorithmspt_BR
dc.subjectAlzheimer Diseasept_BR
dc.subjectAmnesiapt_BR
dc.subjectCognition Disorderspt_BR
dc.subjectCorpus Callosumpt_BR
dc.subjectFemalept_BR
dc.subjectHumanspt_BR
dc.subjectImage Enhancementpt_BR
dc.subjectImage Interpretation, Computer-assistedpt_BR
dc.subjectImaging, Three-dimensionalpt_BR
dc.subjectMagnetic Resonance Imagingpt_BR
dc.subjectMalept_BR
dc.subjectMiddle Agedpt_BR
dc.subjectReproducibility Of Resultspt_BR
dc.subjectSensitivity And Specificitypt_BR
dc.subjectThalamuspt_BR
dc.description.abstractTA is a branch of image processing that seeks to reduce image information by extracting texture descriptors from the image. TA of MR images of anatomic structures in mild AD and aMCI is not well-studied. Our objective was to attempt to find differences among patients with aMCI and mild AD and normal-aging subjects, by using TA applied to the MR images of the CC and the thalami of these groups of subjects. TA was applied to the MR images of 17 patients with aMCI, 16 patients with mild AD, and 16 normal-aging subjects. The TA approach was based on the GLCM. MR images were T1-weighted and were obtained in the sagittal and axial planes. The CC and thalami were manually segmented for each subject, and 44 texture parameters were computed for each of these structures. TA parameters showed differences among the 3 groups for the CC and thalamus. A pair-wise comparison among groups showed differences for AD-control and aMCI-AD for the CC; and for AD-control, aMCI-AD, and aMCI-control for the thalamus. TA is a useful technique to aid in the detection of tissue alterations in MR images of mild AD and aMCI and has the potential to become a helpful tool in the diagnosis and understanding of these pathologies.en
dc.relation.ispartofAjnr. American Journal Of Neuroradiologypt_BR
dc.relation.ispartofabbreviationAJNR Am J Neuroradiolpt_BR
dc.date.issued2011-Janpt_BR
dc.identifier.citationAjnr. American Journal Of Neuroradiology. v. 32, n. 1, p. 60-6, 2011-Jan.pt_BR
dc.language.isoengpt_BR
dc.description.volume32pt_BR
dc.description.firstpage60-6pt_BR
dc.rightsabertopt_BR
dc.sourcePubMedpt_BR
dc.identifier.issn1936-959Xpt_BR
dc.identifier.doi10.3174/ajnr.A2232pt_BR
dc.identifier.urlhttp://www.ncbi.nlm.nih.gov/pubmed/20966061pt_BR
dc.date.available2015-11-27T13:21:48Z-
dc.date.accessioned2015-11-27T13:21:48Z-
dc.description.provenanceMade available in DSpace on 2015-11-27T13:21:48Z (GMT). No. of bitstreams: 1 pmed_20966061.pdf: 648043 bytes, checksum: b19584c6a5debcc4a9120eaf0fd1c340 (MD5) Previous issue date: 2011en
dc.identifier.urihttp://repositorio.unicamp.br/jspui/handle/REPOSIP/199597-
dc.identifier.idPubmed20966061pt_BR
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