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dc.contributor.CRUESPUNIVERSIDADE DE ESTADUAL DE CAMPINASpt_BR
dc.typeArtigo de periódicopt_BR
dc.titleHeart And Liver T2 Assessment For Iron Overload Using Different Software Programs.pt_BR
dc.contributor.authorFernandes, Juliano Lpt_BR
dc.contributor.authorSampaio, Erika Fontanapt_BR
dc.contributor.authorVerissimo, Monicapt_BR
dc.contributor.authorPereira, Fabricio Bpt_BR
dc.contributor.authorda Silva, Jose Alvaropt_BR
dc.contributor.authorde Figueiredo, Gabriel Spt_BR
dc.contributor.authorKalaf, Jose Mpt_BR
dc.contributor.authorCoelho, Otavio Rpt_BR
unicamp.authorJuliano L Fernandes, University of Campinas, Unicamp, Campinas, Brazil. jlaraf@fcm.unicamp.brpt_BR
unicamp.author.externalErika Fontana Sampaio,pt
unicamp.author.externalMonica Verissimo,pt
unicamp.author.externalFabricio B Pereira,pt
unicamp.author.externalJose Alvaro da Silva,pt
unicamp.author.externalGabriel S de Figueiredo,pt
unicamp.author.externalJose M Kalaf,pt
unicamp.author.externalOtavio R Coelho,pt
dc.subjectAdultpt_BR
dc.subjectCross-sectional Studiespt_BR
dc.subjectFemalept_BR
dc.subjectHumanspt_BR
dc.subjectIronpt_BR
dc.subjectIron Overloadpt_BR
dc.subjectLiverpt_BR
dc.subjectMagnetic Resonance Imagingpt_BR
dc.subjectMalept_BR
dc.subjectMyocardiumpt_BR
dc.subjectSoftwarept_BR
dc.subjectBeta-thalassemiapt_BR
dc.description.abstractTo assess the level of agreement and interchangeability among different software programs for calculation of T2 values for iron overload. T2 images were analysed in 60 patients with thalassaemia major using the truncation method in three software programs. Levels of agreement were assessed using Pearson correlation and Bland-Altman plots. Categorical classification for levels of iron concentration by each software program was also compared. For the heart, all correlation coefficients were significant among the software programs (P < 0.001 for all coefficients). The mean differences and 95% limits of agreement were 0.2 (-4.73 to 5.0); 0.1 (-4.0 to 3.9); and -0.1 (-4.3 to 4.8). For the liver all correlations were also significant with P < 0.001. Bland-Altman plots showed differences of -0.02 (-0.7 to 0.6); 0.01 (-0.4 to 0.4); and -0.02 (-0.6 to 0.6). There were no significant differences in clinical classification among the software programs. All tools used in this study provided very good agreement among heart and liver T2 values. The results indicate that interpretation of T2 data is interchangeable with any of the software programs tested. Magnetic resonance imaging in iron overload assessment has become an essential tool. Post processing options to establish T2 values have not been compared. No differences were found on T2 of the liver or heart using 3 different techniques. Availability of these methods should allow more widespread interpretation of iron overload by MRI.en
dc.relation.ispartofEuropean Radiologypt_BR
dc.relation.ispartofabbreviationEur Radiolpt_BR
dc.date.issued2011-Decpt_BR
dc.identifier.citationEuropean Radiology. v. 21, n. 12, p. 2503-10, 2011-Dec.pt_BR
dc.language.isoengpt_BR
dc.description.volume21pt_BR
dc.description.firstpage2503-10pt_BR
dc.rightsfechadopt_BR
dc.sourcePubMedpt_BR
dc.identifier.issn1432-1084pt_BR
dc.identifier.doi10.1007/s00330-011-2208-1pt_BR
dc.identifier.urlhttp://www.ncbi.nlm.nih.gov/pubmed/21842212pt_BR
dc.date.available2015-11-27T13:21:46Z-
dc.date.accessioned2015-11-27T13:21:46Z-
dc.description.provenanceMade available in DSpace on 2015-11-27T13:21:46Z (GMT). No. of bitstreams: 1 pmed_21842212.pdf: 372681 bytes, checksum: 4d0732d2469afc301dcebd14d8f101d4 (MD5) Previous issue date: 2011en
dc.identifier.urihttp://repositorio.unicamp.br/jspui/handle/REPOSIP/199585-
dc.identifier.idPubmed21842212pt_BR
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