Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/197883
Type: Artigo de periódico
Title: 1,5-asymmetric Induction In Boron-mediated Aldol Reactions Of Beta-alkoxy Methylketones.
Author: Dias, Luiz C
de Marchi, Anderson A
Ferreira, Marco A B
Aguilar, Andrea M
Abstract: Good levels of substrate-controlled, 1,5- syn-stereoinduction are obtained in boron-mediated aldol reactions of beta-trichloromethyl-beta-alkoxy and beta-trifluoromethyl-beta-alkoxy methylketones with achiral aldehydes, independent of the nature of the beta-alkoxy protecting group (TBS or PMB). In the case of boron aldol reactions of beta-aryl-beta-alkoxy methylketones, the 1,5- anti-adducts were obtained with high levels of diastereoselectivity only with a beta-OPMB group.
Subject: Alcohols
Aldehydes
Boron Compounds
Ketones
Stereoisomerism
Citationo: The Journal Of Organic Chemistry. v. 73, n. 16, p. 6299-311, 2008-Aug.
Rights: fechado
Identifier DOI: 10.1021/jo8009165
Address: http://www.ncbi.nlm.nih.gov/pubmed/18616322
Date Issue: 2008
Appears in Collections:Artigos e Materiais de Revistas Científicas - Unicamp

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