Please use this identifier to cite or link to this item:
Type: Artigo de periódico
Title: The Relationship Between Abo Groups And Subgroups, Factor Viii And Von Willebrand Factor.
Author: Sousa, Norma Cristina
Anicchino-Bizzacchi, Joyce Maria
Locatelli, Maria Fátima
Castro, Vagner
Barjas-Castro, Maria Lourdes
Abstract: The aim of this study was to correlate ABO groups with plasma levels of factor VIII (FVIII), von Willebrand factor (VWF:Ag), and ristocetin cofactor (VWF:RCo). Serological and molecular tests defined blood groups from 114 donors (10 AA, 10 BB, 10 AB, 10 AO1, 10 BO1,16 O1O1, 20 A2O1, 20 A2B, 4 A3O1, 3 AxO1, and 1 BelO1). The levels of VWF:Ag, FVIII and VWF:RCo observed in rare subgroups (A3O1, AxO1, BelO1) were similar to the values found in the O1O1 group. However, levels of these factors were significantly higher in A2O1 donors than in O1O1 donors (VWF:Ag p=0.01; FVIII p=0.04; VWF:RCo p<0.001). Strong correlations were demonstrated between plasma levels of VWF:Ag and FVIII (R=0.77; p=0.001) and between VWF:Ag and VWF:RCo (R=0.75; p=0.001).
Subject: Abo Blood-group System
Adam Proteins
Factor Viii
Von Willebrand Diseases
Von Willebrand Factor
Citation: Haematologica. v. 92, n. 2, p. 236-9, 2007-Feb.
Rights: aberto
Date Issue: 2007
Appears in Collections:Unicamp - Artigos e Outros Documentos

Files in This Item:
File SizeFormat 
pmed_17296574.pdf404.46 kBAdobe PDFView/Open

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.