Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/197043
Type: Artigo
Title: Fatores prognósticos para ventilação mecânica em lactentes com doença respiratória aguda baixa
Title Alternative: Prognostic factors for mechanical ventilation in infants with acute lower respiratory disease
Author: Riccetto, Adriana Gut Lopes
Baracat, Emílio Carlos Elias
Ribeiro, José Dirceu
Silva, Marcos Tadeu Nolasco da
Abstract: Acute lower respiratory tract infections are the most common cause of hospital admission in pediatrics. A number of admitted patients need invasive mechanical pulmonary ventilation (IMPV). This study aimed to evaluate prognostic factors for IMPV in infants admitted due to acute lower respiratory infection. A prospective cohort study was conducted from April to September, 2004, in two university hospitals of the Campinas metropolitan area, São Paulo, Brazil. One hundred, fifty-two infants were enrolled. Epidemiological and clinical data were recorded at admission and follow-up. Two groups were analyzed, according to the need of IMPV, with a comparison of prognostic factors. Association between risk factors and the outcome were studied and assessed by Relative Risk (RR), with confidence intervals of (95%CI). Twenty-one patients (13.81%) needed IMPV. Factors significantly associated with IMPV on admission were: age < 3 months (RR=2.35, 95%CI:1.06-5.22), breast feeding < 1 month (RR=3.15, 95%CI:1.35-7.35) and cyanosis (RR=7.55, 95%CI:5.01-11.36). In the IMPV group, increased risks for hospitalization > 10 days (RR=13.69, 95%CI:4.92-38.09), oxygen therapy > 10 days (RR=13.57, 95%CI:5.41-34.03), antibiotic usage (RR=3.03, 95%CI:1.34-6.89) and readmission (RR=5.23, 95%CI:2.12-12.91) were observed. The associations between need of IMPV and early age, reduced breast feeding and cyanosis demonstrate diminished physiological reserves in the young infant with lower respiratory infection. These patients require prolonged and intensive hospital support and readmission.
Infecções respiratórias agudas são a causa mais comum de internação hospitalar em pediatria. Uma proporção de pacientes internados necessita de ventilação pulmonar mecânica invasiva (VPMI). Este estudo objetivou avaliar fatores prognósticos para VPMI em lactentes hospitalizados por infecção respiratória aguda baixa. Estudo de coorte prospectivo, realizado de abril a setembro de 2004, em dois hospitais universitários da região de Campinas, São Paulo, Brasil. Foram avaliados 152 lactentes internados, registrando-se dados epidemiológicos e clínicos na internação e no seguimento. Analisaram-se dois grupos, de acordo com a necessidade de VPMI, comparando-se os fatores prognósticos. A associação entre fatores de risco e desfecho estudado foi analisada por risco relativo (RR) e intervalos de confiança (IC 95%). Vinte e um pacientes (13,81%) necessitaram de VPMI. Fatores significativamente associados à VPMI na admissão foram: idade < 3 meses (RR=2,35, IC 95%:1,06-5,22), aleitamento materno < 1 mês (RR=3,15, IC 95%:1,35-7,35) e cianose (RR=7,55, IC 95%:5,01-11,36). Observou-se risco aumentado no grupo de VPMI para internação > 10 dias (RR=13,69, IC 95%:4,92-38,09), oxigenioterapia > 10 dias (RR=13,57, IC 95%:5,41-34,03), uso de antibióticos (RR=3,03, IC 95%:1,34-6,89) e reinternações (RR=5,23, IC 95%:2,12-12,91) CONCLUSÃO: As associações entre a necessidade de VPMI e baixa idade, tempo curto de aleitamento materno e cianose à admissão demonstram as reduzidas reservas fisiológicas no lactente jovem com infecção respiratória baixa. Caracterizam este grupo de pacientes a necessidade de suporte hospitalar prolongado e intensivo e maior taxa de reinternações.
metadata.dc.description.abstractalternative: Acute lower respiratory tract infections are the most common cause of hospital admission in pediatrics. A number of admitted patients need invasive mechanical pulmonary ventilation (IMPV). This study aimed to evaluate prognostic factors for IMPV in infants admitted due to acute lower respiratory infection. A prospective cohort study was conducted from April to September, 2004, in two university hospitals of the Campinas metropolitan area, São Paulo, Brazil. One hundred, fifty-two infants were enrolled. Epidemiological and clinical data were recorded at admission and follow-up. Two groups were analyzed, according to the need of IMPV, with a comparison of prognostic factors. Association between risk factors and the outcome were studied and assessed by Relative Risk (RR), with confidence intervals of (95%CI). Twenty-one patients (13.81%) needed IMPV. Factors significantly associated with IMPV on admission were: age < 3 months (RR=2.35, 95%CI:1.06-5.22), breast feeding < 1 month (RR=3.15, 95%CI:1.35-7.35) and cyanosis (RR=7.55, 95%CI:5.01-11.36). In the IMPV group, increased risks for hospitalization > 10 days (RR=13.69, 95%CI:4.92-38.09), oxygen therapy > 10 days (RR=13.57, 95%CI:5.41-34.03), antibiotic usage (RR=3.03, 95%CI:1.34-6.89) and readmission (RR=5.23, 95%CI:2.12-12.91) were observed. CONCLUSION: The associations between need of IMPV and early age, reduced breast feeding and cyanosis demonstrate diminished physiological reserves in the young infant with lower respiratory infection. These patients require prolonged and intensive hospital support and readmission.
Subject: Criança
Country: Brasil
Editor: Associação Médica Brasileira
Citation: Revista Da Associação Médica Brasileira (1992). v. 52, n. 5, p. 342-6
Rights: aberto
Identifier DOI: 10.1590/S0104-42302006000500023
Address: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-42302006000500023
Date Issue: 2006
Appears in Collections:FCM - Artigos e Outros Documentos

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