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Type: Artigo de periódico
Title: High Expression Of Fmnl1 Protein In T Non-hodgkin's Lymphomas.
Author: Favaro, Patricia M B
Traina, Fabiola
Vassallo, Jose
Brousset, Pierre
Delsol, George
Costa, Fernando F
Saad, Sara T O
Abstract: We recently cloned a novel Formin-family human gene, denominated human leukocyte formin and posteriorly named as FMNL1 by the HUGO Gene Nomenclature Committee. This gene is overexpressed in lymphoid malignances and is found associated with Akt. Here, we describe the expression of the FMNL1 protein in 54 frozen biopsies of non-Hodgkin's lymphoma (NHL) patients and five reactive lymph nodes. Western blot analysis revealed expression of FMNL1 in all samples studied, although the highest expression was in T-cell NHL (P<0.05).
Subject: Adult
Aged, 80 And Over
Blotting, Western
Cytoskeletal Proteins
Gene Expression Regulation, Leukemic
Lymph Nodes
Lymphoma, T-cell
Middle Aged
Neoplasm Proteins
Citation: Leukemia Research. v. 30, n. 6, p. 735-8, 2006-Jun.
Rights: fechado
Identifier DOI: 10.1016/j.leukres.2005.10.003
Date Issue: 2006
Appears in Collections:Unicamp - Artigos e Outros Documentos

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