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Type: Artigo de periódico
Title: [clinical Treatment Of Resistant Epilepsy].
Author: Damasceno, B P
Campos Junior, S da S
Martins, L F
de Melo-Souza, S E
Abstract: The authors analysed 34 cases of resistant epilepsy (20 males and 14 females, mean age 23 years), treated clinically between February/1984 and May/1986. The patients underwent neurological, neuropsychological, psychological, psychiatric, cerebrospinal fluid, electroencephalographic, tomographic and/or angiographic examination. Most of the patients had complex partial seizures. The etiology was unknown in 19 patients (55.8%), probable neurocysticercosis in 6, perinatal hypoxia in 5, delivery trauma in 3 and probable sequelae of encephalitis in 2 patients. There was a clear past history of infantile febrile convulsion in 2 patients. Most patients received carbamazepine (mean dose 24.5 mg/kg/day), phenytoin (5 mg/kg and valproic acid (28 mg/kg) as monotherapy or in association. Twenty-two patients (64.7%) had more than 80% decrease of the seizure frequency. Nine resistant epilepsy cases (24.5%) were evaluated as candidates for surgical therapy. The authors concluded that the resistant epilepsy is best managed by a specialised, multidisciplinary team, and pointed out the need of a correct diagnosis of the seizure type, an adequate drug therapy and a good engagement of the patient and his family in the treatment.
Subject: Adolescent
Drug Resistance
Middle Aged
Patient Compliance
Valproic Acid
Citation: Arquivos De Neuro-psiquiatria. v. 46, n. 4, p. 351-8, 1988-Dec.
Rights: aberto
Date Issue: 1988
Appears in Collections:Unicamp - Artigos e Outros Documentos

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