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dc.typeArtigo de periódicopt_BR
dc.titleShort Stature In Chronic Kidney Disease: Physiopathology And Treatment With Growth Hormone [baixa Estatura Na Doença Renal Crônica: Fisiopatologia E Tratamento Com Hormônio De Crescimento]pt_BR
dc.contributor.authorDe Oliveira J.C.pt_BR
dc.contributor.authorSiviero-Miachon A.A.pt_BR
dc.contributor.authorSpinola-Castro A.M.pt_BR
dc.contributor.authorBelangero V.M.S.pt_BR
dc.contributor.authorGuerra Jr. G.pt_BR
unicamp.authorDe Oliveira, J.C., Clínica Médica, Faculdade de Ciências Médicas (FCM), Universidade Estadual de Campinas (Unicamp), Campinas, SP, Brazilpt_BR
unicamp.authorBelangero, V.M.S., Unidade de Nefrologia Pediátrica, Departamento de Pediatria, FCM-Unicamp, Campinas, SP, Brazilpt_BR
unicamp.authorGuerra Jr., G., Unidade de Endocrinologia Pediátrica, Departamento de Pediatria, FCM-Unicamp, Campinas, SP, Brazil, Departamento de Pediatria, Faculdade de Ciências Médicas, Unicamp, CP 6111, 13083-970 Campinas, SP, Brazilpt_BR, A.A., Programa de Pós-graduação do Curso de Pediatria, Escola Paulista de Medicina (EPM), Universidade Federal de São Paulo (Unifesp), São Paulo, SP, Brazilpt, A.M., Unidade de Endocrinologia Pediátrica, Departamento de Pediatria, EPM-Unifesp, São Paulo, SP, Brazilpt
dc.description.abstractGrowth failure is frequent and a clinically important issue in children with chronic kidney disease (CKD). Many factors contribute to impaired growth in these children, including abnormalities in the growth hormone (GH) - insulin-like growth factor 1 (IGF-1) axis, malnutrition, acidosis, renal bone disease and glucocorticoid associated treatment. The management of growth failure in children with CKD is complicated by the presence of other-disease related complications requiring medical intervention. Despite evidence of GH efficacy and safety in this population, this therapy is still underutilized. This review shows the impact, the causes and the treatment of growth failure in children with CKD. copyright© ABE&M todos os direitos reservados.en
dc.relation.ispartofArquivos Brasileiros de Endocrinologia e Metabologiapt_BR
dc.identifier.citationArquivos Brasileiros De Endocrinologia E Metabologia. , v. 52, n. 5, p. 783 - 791, 2008.pt_BR
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