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Type: Artigo de periódico
Title: Short Stature In Chronic Kidney Disease: Physiopathology And Treatment With Growth Hormone [baixa Estatura Na Doença Renal Crônica: Fisiopatologia E Tratamento Com Hormônio De Crescimento]
Author: De Oliveira J.C.
Siviero-Miachon A.A.
Spinola-Castro A.M.
Belangero V.M.S.
Guerra Jr. G.
Abstract: Growth failure is frequent and a clinically important issue in children with chronic kidney disease (CKD). Many factors contribute to impaired growth in these children, including abnormalities in the growth hormone (GH) - insulin-like growth factor 1 (IGF-1) axis, malnutrition, acidosis, renal bone disease and glucocorticoid associated treatment. The management of growth failure in children with CKD is complicated by the presence of other-disease related complications requiring medical intervention. Despite evidence of GH efficacy and safety in this population, this therapy is still underutilized. This review shows the impact, the causes and the treatment of growth failure in children with CKD. copyright© ABE&M todos os direitos reservados.
Citation: Arquivos Brasileiros De Endocrinologia E Metabologia. , v. 52, n. 5, p. 783 - 791, 2008.
Rights: aberto
Date Issue: 2008
Appears in Collections:Unicamp - Artigos e Outros Documentos

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