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dc.contributor.CRUESPUNIVERSIDADE DE ESTADUAL DE CAMPINASpt_BR
dc.typeArtigo de periódicopt_BR
dc.titlePlasmapheresis As A Therapy For Relapsed Focal Segmental Glomerulosclerosis (fsgs) After Kidney Transplantation: Case Report And A Review Of The Literature [plasmaférese Como Tratamento De Glomeruloesclerose Segmentar Focal (gesf) Recorrente Após Transplante Renal. Relato De Caso E Revisão Da Literatura]pt_BR
dc.contributor.authorMoraes M.C.pt_BR
dc.contributor.authorRoveri E.G.pt_BR
dc.contributor.authorOliveira L.C.pt_BR
dc.contributor.authorRigatto S.Z.P.pt_BR
dc.contributor.authorBelangero V.M.S.pt_BR
dc.contributor.authorMarques Jr. J.F.C.pt_BR
unicamp.authorRoveri, E.G., Centro de Hematologia e Hemoterapia, Universidade Estadual de Campinas (Unicamp), Brazilpt_BR
unicamp.authorRigatto, S.Z.P., Departamento de Pediatria, Universidade Estadual de Campinas, Brazilpt_BR
unicamp.authorBelangero, V.M.S., Departamento de Pediatria, Universidade Estadual de Campinas, Brazilpt_BR
unicamp.authorMarques Jr., J.F.C., Centro de Hematologia e Hemoterapia, Universidade Estadual de Campinas (Unicamp), Brazil, Hemocentro Unicamp, Caixa Postal 6198, 13081-970 - Campinas-SP, Brazilpt_BR
unicamp.author.externalMoraes, M.C.pt
unicamp.author.externalOliveira, L.C.pt
dc.description.abstractFocal segmental glomerulosclerosis (FSGS) is a renal disease characterized by a nephrotic syndrome frequently evolving to endstage renal failure. At this stage, renal transplantation, using either cadaver or live donors, is the only therapeutic option. However, after renal transplantation relapse is high, at a rate of 50% on average. The cause seems to be related to a peripheral humoral factor responsible for increasing glomerular permeability. The clearance of this factor by apheresis is today considered a good therapeutic option. We describe the case of a 12-year-old male patient, with relapsed FSGS after renal transplantation, who was treated by plasmapheresis. After five procedures a sustained improvement in the renal function was obtained. Reports published on plasmapheresis for the treatment of FSGS before and after renal transplantation are still limited to short-term results involving a small number of patients. Some predictive factors for good responses were identified by several investigators including the early start of treatment after relapse and lower ages. The number of plasmapheretic procedures to reach remission varies widely, and should be determined on a case to case basis. Another possibility presented by some investigators is prophylactic plasmapheresis, but this still lacks evidence on efficacy. This case report is an example of FSGS with a good response to plasmapheretic procedures, showing a potential benefit of this treatment. However, further controlled studies involving a higher number of patients are necessary.en
dc.relation.ispartofRevista Brasileira de Hematologia e Hemoterapiapt_BR
dc.date.issued2007pt_BR
dc.identifier.citationRevista Brasileira De Hematologia E Hemoterapia. , v. 29, n. 2, p. 193 - 197, 2007.pt_BR
dc.language.isoptpt_BR
dc.description.volume29pt_BR
dc.description.issuenumber2pt_BR
dc.description.firstpage193pt_BR
dc.description.lastpage197pt_BR
dc.rightsabertopt_BR
dc.sourceScopuspt_BR
dc.identifier.issn15168484pt_BR
dc.identifier.doi10.1590/S1516-84842007000200020pt_BR
dc.identifier.urlhttp://www.scopus.com/inward/record.url?eid=2-s2.0-37349115286&partnerID=40&md5=b0022e9ff360a5b713a3e8a988027205pt_BR
dc.date.available2015-06-30T18:51:09Z
dc.date.available2015-11-26T14:38:42Z-
dc.date.accessioned2015-06-30T18:51:09Z
dc.date.accessioned2015-11-26T14:38:42Z-
dc.description.provenanceMade available in DSpace on 2015-06-30T18:51:09Z (GMT). No. of bitstreams: 1 2-s2.0-37349115286.pdf: 65872 bytes, checksum: 7f50905c6f73a0792360a9d82c4c1092 (MD5) Previous issue date: 2007en
dc.description.provenanceMade available in DSpace on 2015-11-26T14:38:42Z (GMT). No. of bitstreams: 1 2-s2.0-37349115286.pdf: 65872 bytes, checksum: 7f50905c6f73a0792360a9d82c4c1092 (MD5) Previous issue date: 2007en
dc.identifier.urihttp://www.repositorio.unicamp.br/handle/REPOSIP/105083
dc.identifier.urihttp://repositorio.unicamp.br/jspui/handle/REPOSIP/105083-
dc.identifier.idScopus2-s2.0-37349115286pt_BR
dc.description.referenceWehrmann, M., Bohle, A., Held, H., Schumm, G., Kendziorra, H., Pressler, H., Long-term prognosis of focal sclerosing glomerulonephritis. An analysis of 250 cases with particular regard to tubulointerstitial changes (1990) Clin Nephrol, 33 (3), pp. 115-122pt_BR
dc.description.referenceDatta, A.R., Sakhuja, V., Minz, M., Joshi, K., Chugh, K.S., Recurrent focal segmental glomerulosclerosis after renal transplantation (1991) Int J Artif Organs, 14 (2), pp. 99-101pt_BR
dc.description.referenceArtero, M., Biava, C., Amend, W., Tomlanovich, S., Vincenti, F., Recurrent focal glomerulosclerosis: Natural history and response to therapy (1992) Am J Med, 92 (4), pp. 375-383pt_BR
dc.description.referenceGarcia, V., Abbud-Filho, M., Keitel, E., Neumann, J., Goldani, J.C., Recurrent focal glomerulosclerosis in renal allografts (1995) Transplant Proc, 27 (1), pp. 1084-1085pt_BR
dc.description.referenceKim, E.M., Striegel, J., Kim, Y., Matas, A.J., Najarian, J.S., Mauer, S.M., Recurrence of steroid-resistant nephrotic syndrome in kidney transplants is associated with increased acute renal failure and acute rejection (1994) Kidney Int, 45 (5), pp. 1440-1445pt_BR
dc.description.referenceStephanian, E., Matas, A.J., Mauer, S.M., Chavers, B., Nevins, T., Kashtan, C., Recurrence of disease in patients retransplanted for focal segmental glomerulosclerosis (1992) Transplantation, 53 (4), pp. 755-757pt_BR
dc.description.referenceSavin, V.J., Sharma, R., Sharma, M., McCarthy, E.T., Swan, S.K., Ellis, E., Circulating factor associated with increased glomerular permeability to albumin in recurrent focal segmental glomerulosclerosis (1996) N Engl J Med, 334 (14), pp. 878-883pt_BR
dc.description.referenceSharma, M., Sharma, R., McCarthy, E.T., Savin, V.J., The FSGS factor: Enrichment and in vivo effect of activity from focal segmental glomerulosclerosis plasma (1999) J Am Soc Nephrol, 10 (3), pp. 552-561pt_BR
dc.description.referenceMatalon, A., Valeri, A., Appel, G.B., Treatment of focal segmental glomerulosclerosis (2000) Semin Nephrol, 20 (3), pp. 309-317pt_BR
dc.description.referenceGreenstein, S.M., Delrio, M., Ong, E., Feuerstein, D., Schechner, R., Kim, D., Plasmapheresis treatment for recurrent focal sclerosis in pediatric renal allografts (2000) Pediatr Nephrol, 14 (12), pp. 1061-1065pt_BR
dc.description.referenceOhta, T., Kawaguchi, H., Hattori, M., Komatsu, Y., Akioka, Y., Nagata, M., Effect of pre-and postoperative plasmapheresis on posttransplant recurrence of focal segmental glomerulosclerosis in children (2001) Transplantation, 71 (5), pp. 628-633pt_BR
dc.description.referenceBelson, A., Yorgin, P.D., Al-Uzri, A.Y., Salvatierra, O., Higgins, J., Alexander, S.R., Long-term plasmapheresis and protein A column treatment of recurrent FSGS (2001) Pediatr Nephrol, 16 (12), pp. 985-989pt_BR
dc.description.referenceMatalon, A., Markowitz, G.S., Joseph, R.E., Cohen, D.J., Saal, S.D., Kaplan, B., Plasmapheresis treatment of recurrent FSGS in adult renal transplant recipients (2001) Clin Nephrol, 56 (4), pp. 271-278pt_BR
dc.description.referenceDall'Amico, R., Ghiggeri, G., Carraro, M., Artero, M., Ghio, L., Zamorani, E., Prediction and treatment of recurrent focal segmental glomerulosclerosis after renal transplantation in children (1999) Am J Kidney Dis, 34 (6), pp. 1048-1055pt_BR
dc.description.referenceCheong, H.I., Han, H.W., Park, H.W., Ha, I.S., Han, K.S., Lee, H.S., Early recurrent nephrotic syndrome after renal transplantation in children with focal segmental glomerulosclerosis (2000) Nephrol Dial Transplant, 15 (1), pp. 78-81pt_BR
dc.description.referencePradhan, M., Petro, J., Palmer, J., Meyers, K., Baluarte, H.J., Early use of plasmapheresis for recurrent post-transplant FSGS (2003) Pediatr Nephrol, 18 (9), pp. 934-938pt_BR
dc.description.referenceDantal, J., Baatard, R., Hourmant, M., Cantarovich, D., Buzelin, F., Soulillou, J.P., Recurrent nephrotic syndrome following renal transplantation in patients with focal glomerulosclerosis. A one-center study of plasma exchange effects (1991) Transplantation, 52 (5), pp. 827-831pt_BR
dc.description.referencePonticelli, C., Campise, M., Tarantino, A., The different patterns of response to plasmapheresis of recurrent focal and segmental glomerulosclerosis (2002) Transplant Proc, 34 (8), pp. 3069-3071pt_BR
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