Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/101471
Type: Artigo
Title: Cariogenicity of different types of milk: an experimental study using animal model.
Title Alternative: Cariogenicidade de diferentes tipos de leite - Estudo experimental usando modelo animal
Author: Peres, R. C.
Coppi, L. C.
Franco, E. M.
Volpato, M. C.
Groppo, F. C.
Rosalen, P. L.
Abstract: This study evaluated the cariogenic potential of infant formulas and cow's milk, using a high cariogenic challenge in the animal model. Sixty female Wistar rats infected with Streptococcus sobrinus and desalivated were randomly divided into 6 groups, which received ad libitum: 1) sterilized deionized distilled water (SDW) with 5% sucrose; 2) cow's milk; 3) Nan 2; 4) Nestogeno 2; 5) Ninho growth supporting; 6) SDW. Groups 1 and 6 also received essential diet NCP#2 by gavage, twice a day. After 21 days, the animals were killed and evaluated according to recovered oral microbiota and caries score by using a modified Keyes method. The analysis of the carbohydrates in the milk samples was performed using HPLC. The results were analyzed by Shapiro-Wilk and Kruskal-Wallis tests. Cow's milk had the lowest cariogenic potential compared to the other test groups, but it was not statistically different from group 6. The percentage of S. sobrinus obtained from the oral cavity of the animals was not statistically different among the groups studied, except for the SDW group. It was concluded that cow's milk was not cariogenic and infant formulas showed some cariogenic potential.
This study evaluated the cariogenic potential of infant formulas and cow's milk, using a high cariogenic challenge in the animal model. Sixty female Wistar rats infected with Streptococcus sobrinus and desalivated were randomly divided into 6 groups, which received ad libitum: 1) sterilized deionized distilled water (SDW) with 5% sucrose; 2) cow's milk; 3) Nan 2; 4) Nestogeno 2; 5) Ninho growth supporting; 6) SDW. Groups 1 and 6 also received essential diet NCP#2 by gavage, twice a day. After 21 days, the animals were killed and evaluated according to recovered oral microbiota and caries score by using a modified Keyes method. The analysis of the carbohydrates in the milk samples was performed using HPLC. The results were analyzed by Shapiro-Wilk and Kruskal-Wallis tests. Cow's milk had the lowest cariogenic potential compared to the other test groups, but it was not statistically different from group 6. The percentage of S. sobrinus obtained from the oral cavity of the animals was not statistically different among the groups studied, except for the SDW group. It was concluded that cow's milk was not cariogenic and infant formulas showed some cariogenic potential
metadata.dc.description.abstractalternative: Este estudo avaliou o potencial cariogênico de fórmulas infantis e do leite de vaca, usando um modelo de alto desafio cariogênico em animais. Sessenta ratas Wistar infectadas com Streptococcus sobrinus e dessalivadas foram aleatoriamente dividas em 6 grupos os quais receberam ad libitum: (1) água destilada e esterelizada (ADE) com 5% de sacarose; (2) leite bovino tipo A; (3) Nan 2®; (4) Nestogeno 2®; (5) Ninho® coadjuvante de crescimento; (6) ADE. Os grupos 1 e 6 também receberam dieta essencial NCP#2, através de gavage, 2 vezes/dia. Após 21 dias, os animais foram sacrificados e avaliados quanto a microbiota oral recuperada e o índice de cárie de Keyes modificado. A análise dos carboidratos nos leites foi feita através de CLAE. Os resultados foram submetidos aos testes de Shapiro-Wilk e Kruskal-Wallis. O leite bovino apresentou o menor potencial cariogênico quando comparado aos outros grupos testes, porém não diferiu estatisticamente do grupo 6. As porcentagens de S. sobrinus dos grupos 1 a 5 não apresentaram diferenças estatisticamente significantes entre si, exceto em relação ao grupo 6. Concluímos que o leite bovino não foi cariogênico e as fórmulas infantis mostraram potencial cariogênico
Subject: Cárie dentária
Leite
Ratos
Country: Brasil
Editor: USP/Fundação Odontológica de Ribeirão Preto
Citation: Brazilian Dental Journal. , v. 13, n. 1, p. 27 - 32, 2002.
Rights: aberto
Address: https://www.forp.usp.br/bdj/bdj13(1)/trab05131/trab05131.html
Date Issue: 2002
Appears in Collections:FOP - Artigos e Outros Documentos

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